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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 29.09
Human Site: S562 Identified Species: 49.23
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 S562 R E R R F H P S L R S T R R F
Chimpanzee Pan troglodytes XP_001162276 812 89269 S562 Q E R R F H P S L R S T R R F
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 S561 R E R R F H P S L R S A R R F
Dog Lupus familis XP_854432 985 108067 T733 R E R R F H P T L R S T R R F
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 T547 Q A R R F H P T L R S T R R F
Rat Rattus norvegicus XP_235295 772 84951 T542 R E R R F H P T L R A T R R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 F455 F P K V L G G F D R V L L D A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 E491 R S A H L Q K E L I L S A I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 S613 R Q H R F H P S L N L T K R Y
Honey Bee Apis mellifera XP_001121968 582 67009 L355 L Q G A S S F L P V M A L D P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 S839 K A R H F H P S L K L S R R I
Poplar Tree Populus trichocarpa XP_002300386 476 53332 V249 K T L G L N T V D R V L L D A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 I444 T S K S A D D I K K F A H L Q
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 H391 K S L I A N I H R L G C T N T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 93.3 93.3 93.3 N.A. 80 86.6 N.A. N.A. 6.6 N.A. 13.3 N.A. 60 0 N.A. 53.3
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 100 N.A. N.A. 13.3 N.A. 20 N.A. 80 6.6 N.A. 73.3
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 0 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 8 15 0 0 0 0 0 8 22 8 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 0 15 0 0 0 0 22 8 % D
% Glu: 0 36 0 0 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 58 0 8 8 0 0 8 0 0 0 43 % F
% Gly: 0 0 8 8 0 8 8 0 0 0 8 0 0 0 0 % G
% His: 0 0 8 15 0 58 0 8 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 8 0 0 8 8 0 8 0 0 0 8 8 % I
% Lys: 22 0 15 0 0 0 8 0 8 15 0 0 8 0 0 % K
% Leu: 8 0 15 0 22 0 0 8 65 8 22 15 22 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 15 0 0 0 8 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 0 58 0 8 0 0 0 0 0 8 % P
% Gln: 15 15 0 0 0 8 0 0 0 0 0 0 0 0 8 % Q
% Arg: 43 0 50 50 0 0 0 0 8 58 0 0 50 58 0 % R
% Ser: 0 22 0 8 8 8 0 36 0 0 36 15 0 0 0 % S
% Thr: 8 8 0 0 0 0 8 22 0 0 0 43 8 0 8 % T
% Val: 0 0 0 8 0 0 0 8 0 8 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _